Nidogen
Nidogen (entaktyna) (masa cząsteczkowa 150kDa) – usiarczanowana glikoproteina wchodząca w skład wszystkich błon podstawnych. Występuje w blaszce jasnej błony. Ma 3 domeny globularne. Od końca N dwie mniejsze G1 i G2 i na końcu C większą G3. Pomiędzy domenami G2 i G3 jest długa pałeczka zawierająca powtórzone sekwencje przypominające EGF (czynnik wzrostu naskórka)
G2 odpowiada za łączenie się nidogenu z włóknami Kolagenu IV
G3 odpowiada za łączenie się nidogenu z łańcuchem B2[γ] Laminy
Fizjologicznie jest łącznikiem pomiędzy integrynami plazmalemmy i kolagenem typu IV, który stanowi blaszkę gęstą błony podstawnej oraz lamininą.
Nidogen.jpg

Jest to fragment artykułu Nidogen z darmowej encyklopedii Wikipedia. Na Wikipedii dostępna jest lista autorów.
Na pl.wikipedia.org artykuł Nidogen był wyświetlany 98 razy w ciągu ostatnich 30 dni. (Stan z dnia: 01.07.2014)
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Nidogen – Wikipedia, wolna encyklopedia
Nidogen (entaktyna) (masa cząsteczkowa 150kDa) – usiarczanowana glikoproteina wchodząca w skład wszystkich błon podstawnych. Występuje w blaszce ...
pl.wikipedia.org/wiki/Nidogen
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Entactin - Wikipedia, the free encyclopedia
Entactin also known as Nidogen-1 (NID-1) is a protein that in humans is encoded by the NID1 gene. Entactin is a component of the basement membrane ...
en.wikipedia.org/wiki/Entactin
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Nidogen-1 and nidogen-2 are found in basement membranes ...
The recently identified Nidogen-2 is a matrix protein showing homology to the well-known basement membrane molecule Nidogen-1. Nidogen-1 might well serve ...
www.ncbi.nlm.nih.gov/pubmed/12005023
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Nidogen-1/Entactin - R&D Systems - Products
Nidogen-2 (also called entactin-2) is a 200 kDa, secreted, basement membrane glycoprotein. Nidogens-1 and -2 are expressed in nearly all basement ...
www.rndsystems.com/molecule_detail.aspx?m=2695
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Basement Membrane Deposition of Nidogen 1 but Not Nidogen 2 ...
21 Jan 2011 ... The Nidogen-laminin interaction is proposed to play a key role in basement membrane (BM) assembly. However, though there are similarities, ...
www.jbc.org/content/286/3/1911.full
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Nidogen and tissue-specific gene expression - Journal of Cell Science
sulfate proteoglycans and Nidogen-1, and forms a barrier that physically ... In an epithelial cell line containing mesenchymal cells, Nidogen-1 was produced.
jcs.biologists.org/content/113/5/849.full.pdf
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Anti-Nidogen, clone JF3 - Millipore
Western blot: Recognizes native and denatured Nidogen. This antibody is able to block the binding of Nidogen to laminin. ELISA Optimal working dilutions must ...
www.millipore.com/catalogue/item/mab1883
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Anti-Nidogen Antibody, clone ELM1 | MAB1946 - Millipore
This Anti-Nidogen Antibody, clone ELM1 is validated for use in DB, IP, WB, IH for the detection of Nidogen.
www.millipore.com/catalogue/item/mab1946
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Nidogen-1 precursor - Homo sapiens (Human) - UniProt
Contains 4 LDL-receptor class B repeats. Contains 1 NIDO domain. Contains 1 Nidogen G2 beta-barrel domain. Contains 1 thyroglobulin type-1 domain.
www.uniprot.org/uniprot/P14543
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Nidogen Antibody / Nidogen Antibodies | Santa Cruz Biotech
Buy Nidogen antibodies from Santa Cruz. Select a Nidogen antibody from 9 monoclonal and 8 polyclonal antibodies. Nidogen si/shRNA products also available.
www.scbt.com/table-nidogen.html
Wyniki wyszukiwania dla "Nidogen"
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Nidogen w nauce
Anti-Nidogen Rabbit pAb - Produkty - Biotechnologia.pl - łączymy ...
Anti-Nidogen Rabbit pAb ... Krajem, Kierownikiem Katedry Teologii Życia na Wydziale Teologicznym Uniwersytetu Papieskiego Jana Pawła II w Krakowie ...
Cytobiochemia - IBUK Libra - Ibuk.pl
Cykl komórkowy i Śmierć komórki - apoptoza. Większość zmian dokonali pracownicy naukowi Katedry Cytobiochemii Uniwersytetu Łódzkiego, wychowankowie ...
[PDF]Zeszyt 1 - Postępy Mikrobiologii - PTM
Instytut Mikrobiologii, Wydzia³ Biologii, Uniwersytet Warszawski ul. Miecznikowa 1, 02-096 ...... kiem E. faecium wiążącym Nidogen, sk³adnik wszyst- kich b³on ...
[PDF]pełna wersja w pdf - Mediton
1/ Katedra i Klinika Dermatologii i Wenerologii Uniwersytetu Medycznego w £ odzi, 94-017 Łódź, ul. ..... BM-40/osteonektyna/SPARK i Nidogen/entaktyna [29].
[PDF]pełna wersja w pdf - Mediton
1/ Klinika i Katedra Dermatologii i Wenerologii Uniwersytetu Medycznego w £ odzi. 2/ Zak³ad ..... Nidogen as the amine acceptor in transglutaminase-catalyzed.
[PDF]Justyna Gornowicz-Porowska - Poznań
Uniwersytetu Medycznego im. K. Marcinkowskiego w ...... 2003). Nidogen jest w stanie łączyć kompleksy lamininy 6 i 10 do sieci kolagenu IV. W obrębie błony ...
Uniwersytet Medyczny w Bialymstoku. Program nauczania.
27 Wrz 2013 ... Uniwersytet Medyczny w Białymstoku › Wydział Lekarski › Zakład .... elastyna, laminina, Nidogen, proteoglikany i glikozoaminoglikany, budowa ...
[PDF]ANNALES ACADEMIAE MEDICAE GEDANENSIS TOM XXXX 2 0 1 ...
Senackiej Komisji Wydawnictw Gdańskiego Uniwersytetu Medycznego ...... Nidogen 1. Rn.105658 plastyczność neuronalna, rozwój OUN, neurogeneza. 4.
Skin Basement Membrane: The Foundation of Epidermal Integrity ...
21 Mar 2013 ... Biblioteka Otwartego Uniwersytetu ... of Epidermal Integrity—BM Functions and Diverse Roles of Bridging Molecules Nidogen and Perlecan.
Artykuł oryginalny Ekspresja wybranych integryn i selektyn w ...
Na wykonanie badań uzyskano zgodę Komisji Etyki Uniwersytetu ..... Aeschliman D, Paulsson M, Mann K. Identification of Gln726 in Nidogen as the amine ...
Książki na temat Nidogen
Basement Membranes: Cell and Molecular Biology
Basement Membranes: Cell and Molecular Biology
Nicholas A. Kefalides, Jacques P. Borel, 2005
THE ROLE OF ENTACTIN/Nidogen Entactin/Nidogen is an integral component of basement membranes. Invertebrates possess only a single Nidogen gene ( Hutter et al., 2000), whereas mammals have two genes, named entactin/Nidogen- 1 ...
ADVANCES IN PROTEIN CHEMISTRY
ADVANCES IN PROTEIN CHEMISTRY
Christian B. Anfinsen, 1988
Nidogen was initially isolated from the El-IS tumor as a fragment (Mr 80K) that appeared by electron microscopy as an 8- to 10-nm globule with a short tail (10- 14 nm) (Timpl et al., 1983a). It received the name Nidogen on the basis of its ability ...
Assembly of the Vasculature and Its Regulation
Assembly of the Vasculature and Its Regulation
Robert J. Tomanek, 2002
Further studies of the ECM by different laboratories identified a protein with similar characteristics that was termed Nidogen (Chung and Durkin, 1990). Complementary DNA (cDNA) cloning of these proteins eventually revealed that they were ...
The Sticky Synapse: Cell Adhesion Molecules and Their Role ...
The Sticky Synapse: Cell Adhesion Molecules and Their Role ...
Michael Hortsch, Hisashi Umemori, 2009
Nidogens (also previously called entactins) are sulfated monomeric glycoproteins and constitute the fourth core component of BLs. Like laminins, collagen IV, and HSPGs, Nidogens play both structural and bioactive roles in BL assembly and ...
Dynamics of Bone and Cartilage Metabolism: Principles and ...
Dynamics of Bone and Cartilage Metabolism: Principles and ...
Markus J. Seibel, Simon P. Robins, John P. Bilezikian, 2006
MMP No Mr enzyme Mr latent Active Known substrates MMP-1 Interstitial collagenase-1 55 000 45 000 Collagens I, II, III, VII, VIII, X; gelatin: aggrecan, versican, proteoglycan link protein; laminin; perlecan; Nidogen, α1-proteinase inhibitor, α2- ...
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Wpisy na blogach na temat
Nidogen
Basement Membrane Deposition of Nidogen 1 but Not Nidogen 2 Requires the Nidogen Binding Module of the Laminin γ1 Chain
www.jbc.org/content/286/3/1911.abstract
Molecular Cancer | Full text | Nidogen 1and 2gene promoters are aberrantly methylated in human gastrointestinal cancer
Nidogens are highly conserved proteins of basement membranes. Two Nidogen proteins, Nidogen 1 and Nidogen 2, are known in mammals.
www.molecular-cancer.com/content/6/1/17
Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk
hmg.oxfordjournals.org/content/early/2011/04/09/hmg.ddr154
iPage
www.newpharmacy.info/different-domains-in-nidogen-1-and-nidogen-2-drive-basement-membrane-formation-in-skin-organotypic-cocultures-research-communications/
Express and Clinical Significance of Nidogen-1 and Nidogen-2 in Ovarian Epithelial Tumors | Best Medical Research Papers For Sale
Objective:To research the expression of the Nidogen-2 as a new ovarian serous carcinoma biomarker in serum of patients, and to explore the value of the combination of Nidogen-2 and carbohydrateantigenl25 (CA125) in ovarian serous tumor diagnosis. Methods:Nidogen-2 was measured by immunoassay in serum of 40 women with ovarian serous carcinoma.22 women with ovarian serous cystadenoma and 15 ovarian healthy women, meanwhile, monitoring the level of serum CA125 by chemiluminescent immunoassay (CLIA)
www.res-medical.com/oncology/112736
Endocrinology News Article | Lack of nidogen-2 increases blood pressure, glomerular and tubulointerstitial damage in DOCA-salt hypertension |2570263
Endocrinology Medical Article: Lack of Nidogen-2 increases blood pressure, glomerular and tubulointerstitial damage in DOCA-salt hypertension
www.mdlinx.com/endocrinology/news-article.cfm/2570263/hypertension
Skin Basement Membrane: The Foundation of Epidermal Integrity—BM Functions and Diverse Roles of Bridging Molecules Nidogen and Perlecan
BioMed Research International (formerly titled Journal of Biomedicine and Biotechnology) is a peer-reviewed, open access journal that publishes original research articles as well as review articles in several areas of life sciences. The journal’s Editorial Board is divided into the 55 subject areas included within the journal’s scope.
www.hindawi.com/journals/bmri/2013/179784/
abstract: Clinical Biochemistry : Nidogen-2: A new serum biomarker for ovarian cancer (multinational study) Ovarian Cancer and Us OVARIAN CANCER and US Ovarian Cancer and Us
Conclusions:Nidogen-2 is a new biomarker for ovarian cancer which correlates closely with CA125. .
ovariancancerandus.blogspot.com/2010/06/abstract-clinical-biochemistry-nidogen.html
whgatt: Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on Nidogen-1 and Nidogen-2.
llssg.blogspot.com/2013/05/contribution-of-adamts1-as-tumor.html
Poniedziałek...znowu...:)
subiektywnaplytoteka.blox.pl/2010/07/Poniedzialekznowu.html
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